Mesotherapy is a treatment that stimulates the Giant fibers in the horse's mesoderm, the middle layer of skin, which will in turn relieve a wide variety of symptoms.  The technique involves injecting a mixture of substances to stimulate the mesoderm for various biological purposes.  The injections involve extremely small needles that penetrate the inter-dermal layer of the skin only a very small depth, which is typically four to six millimeters.  This is performed standing under sedation, and can be performed on an ambulatory basis.  

The number of treatments necessary to achieve the desired result depends on many variables including the condition, the abnormal physiology causing the condition, and the chronicity of the problem.  On average, a minimum of one to two sessions will be performed to assess your horse's response.  After the injections, the horse should not be ridden for 5-7 days, but can be exercised on a lunge line.